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An interpenetrating polymer network (IPN) is any material containing two polymers, each in network form. An IPN is a combination of at least two polymers, and IPN can produce synergistic effect by sharing the properties of both the polymers consequently avoiding the limitations of natural as well as synthetic polymers. The present review discusses various types of IPN. Various methods of preparation and advantages on IPN are elaborated. The concepts of high swelling capacity, specificity and sensitivity of IPN play an important role in targeting delivery of drugs. IPN has various advantages as a biomaterial and is widely used as carrier systems for delivery of the short biological half life drugs. ISSN: 2277-8713 IJPRBS , Andhra PAPER-QR CODE Review Article ISSN: 2277-8713 Margaret Mercy, IJPRBS, 2013; Volume 2(3): 215-224 IJPRBS Available Online At www.ijprbs.com INTRODUCTION: During the past decades, a diversity of polymer-based pharmaceutical carrier systems have been developed as a new means of the controlling temporal or distributional drug delivery [1]. These controlled drug release systems offer numerous advantages in comparison with conventionally administered drugs in dosage forms, such as improved efficiency and reduced toxicity. Polymeric crosslinked carrier matrices, such as micro particles, hydro gels and supra molecular polymer aggregates are typical examples of common drug delivery devices. INTERPENETRATING POLYMER NETWORK (IPN): An interpenetrating polymer network (IPN) is any material containing two polymers, each in network form. An IPN is a composite of at least two polymers, exhibiting varied characteristics, which is obtained when at least one polymer network is synthesized or cross linked independently in the immediate presence of the other or in other words [2]. An IPN is a combination of at least two polymers chains each in network form, of which at least one is synthesized. The three conditions for eligibility as an IPN are as follows: 1. The two polymers are synthesized or cross linked in the presence of the other. 2. The two polymers have similar kinetics. 3. The two polymers are not dramatically phase separated.